Biological monitoring focuses on the elucidation of the first step of this process i.e., the relationship between environmental exposure and internal dose. This continuum between exposure to organic solvents and disease can be depicted, in a simplified way, in Figure 14.2.1.1. Cellular repair mechanisms and individual susceptibility have a significant effect on the onset of disease, resulting in a broad distribution of outcomes. The dose at the target organ may trigger mechanisms that eventually may result in irreversible biological changes and disease. All sources and routes of exposure are integrated in the resulting internal dose. The magnitude of exposures, however, may be modulated by factors such as the use of protective equipment (decrease) or physical exertion (increase). Solvents reach the organism through inhalation, ingestion and dermal exposure. In addition to the pollution of the internal environment by mist, upon its release to the outdoor atmosphere it can cause damage to air, water, and plants.Įxposure to organic solvents may occur as a result of occupation, diet, lifestyles, hobbies, etc., in a variety of environments (occupational, residential, ambient). Mist-related illness forces the operator to take sick leave, which directly disrupts production ( 61). In some cases, mist generation is minimized by reducing the feeds and speeds, which also affects productivity. Mist will affect the operation of air-conditioning and heating systems, which causes increased energy consumption. Costs of replacing the malfunctioning parts need to be considered as well. Mists settled on sensitive electronics parts, which control the machine operation, can cause malfunctioning of the machine and disrupt production. Over time, the accumulation of oil mist in the work atmosphere increases fire hazard. Oil mist also makes floors and work surfaces slippery, which increases the risk of accident. This will increase cleaning and maintenance costs. Therefore, frequent cleaning of the shop floor and machines is necessary. Mists settle on every part of the machines and everywhere on the shop floor. Repeated and prolonged exposure to mists can increase statistically significant risks of different types of cancer, including esophagus, stomach, pancreas, colon, prostate, and rectum, as found by other studies ( 70, 71). Epidemiological investigation into the potential health effects of cutting fluid mists has suggested that they may cause chronic bronchitis, asthma, or hypersensitivity pneumonitis and loss of lung function ( 69). However, the smaller droplets can go through the nose and settle down into the lungs. Mists are swallowed through the mouth and the larger droplets pass into the nose. #4 gas monitor in breathing zone skinEye, nose, throat, and skin irritation are common health problems when the human body is exposed to mists ( 25, 30, 33). Three agents, including neat fluid, microbial contaminants, and other chemical contaminants of the fluids, are the sources of inhalation hazards ( 30). Oil mists are suspended in the air, possibly in workers' breathing zones the sizes are small enough to be easily inhaled by the operators, causing a number of diseases. Hashmi, in Comprehensive Materials Processing, 2014 8.02.3.3.2.2 Health and environmental impacts b Obtained from EPA On-Line Tools for Site Assessment. Calculated conc in vapor above floating oil (g/L 25☌)īenzo( b)naphtho(2,3-D)thiophene, 7,8-dimethyl-Ī Used to represent numerous isomers comprising each alkyl group.
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